You want power? How deep are your pockets? That's the question. An engine is an air pump, more air in and out, more power. When it comes to power production, head flow is everything. If I had a Buick 350 that I wanted impressive power out of, I would wait a little longer for TA Performance to come out with their aluminum heads. I have the TA heads on my big block Buick. Those heads are the biggest contributor to the power I get from that 470. My first 455 ran low 13's with a KB118 cam and Mickey Thompson headers. Just bolting those heads on to my existing short block dropped my 1/4 mile times by over a second and boosted my traps speed 11 MPH. That is in a 4200 lb. car.
Your 79 Buick 350 is a wheezer because of the pitiful compression (less than 8:1). Add to that the rear gear is probably a 2.41, a heavy curb weight, and that car can't get out of it's own way. The single exhaust and catalytic converter don't help things.
The best way is to get the aluminum heads, get the compression to 10:1, and choose a cam. Yes, you can easily run 10:1 on pump gas with the aluminum heads. Read up on the relationship between static compression and cam timing.
http://www.empirenet.com/pkelley2/DynamicCR.html
Get some 3 series gears out back with the appropriate stall converter, put a true dual exhaust on it, and you'll think you are driving a different car.
Again, this takes money. If you don't have it, put off your plans and start saving to do it right.